Evidence map›Paper›PMID 42312037›Full record

ReviewFrontiers in cellular and infection microbiology2026

Rethinking ethanol consumption and colorectal carcinogenesis: an insight from diet and gut microbiota.

Eva Gómez-Pérez, Sergio Ruiz-Saavedra, Aida Zapico, Adolfo Suárez, Ylenia Diaz, Carmen González Del Rey, Nuria Salazar, Sonia González, Clara G de Los Reyes-Gavilán

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eva Gómez-PérezDepartment of Functional Biology, University of Oviedo, Oviedo, Spain.
Sergio Ruiz-SaavedraDiet, Microbiota and Health Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.
Aida ZapicoDepartment of Functional Biology, University of Oviedo, Oviedo, Spain.
Adolfo SuárezDiet, Microbiota and Health Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.
Ylenia DiazDigestive Service, Carmen and Severo Ochoa Hospital, Cangas del Narcea, Spain.
Carmen González Del ReyDepartment of Anatomical Pathology, Central University Hospital of Asturias (HUCA), Oviedo, Spain.
Nuria SalazarDiet, Microbiota and Health Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.
Sonia GonzálezDepartment of Functional Biology, University of Oviedo, Oviedo, Spain.
Clara G de Los Reyes-GavilánDiet, Microbiota and Health Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a pathology highly influenced by lifestyle and dietary habits, with ethanol consumption recognized as one of the most impactful and modifiable risk factors. Intestinal microbiota alterations have been observed both in high alcohol consumers and in the progression of intestinal polyps to CRC. The diet-microbiota-host interplay has a key role in health and disease. This perspective critically evaluates the mechanistic interplay within this triad and its potential role in mediating alcohol-induced toxicity, as well as its implications for the etiological link between alcohol consumption and CRC risk. Furthermore, we synthesize current advances and delineate key challenges for future research in this area. A particular focus is posed on the analysis of the anatomopathological, nutritional and microbiota data collected from individuals with intestinal polyps in a pilot study carried out in the region of Asturias, Northern Spain.

Indexed as

Alcohol DrinkingCarcinogenesisColorectal NeoplasmsDietGastrointestinal MicrobiomeAnimalsEthanolHumansIntestinal PolypsRisk FactorsSpainEthanolacetaldehydealcoholcolorectal cancerconventional adenomasdietary fibreethanolintestinal polypsmicrobiota

Identifiers

PMID42312037
PMCPMC13269019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.