ArticleEuropean heart journal. Imaging methods and practice2026
Controlled hyperventilation using a new ventilation navigator software: a feasibility study to provoke hypocapnia and respiratory alkalosis: A proposal for coronary artery vasoreactivity assessment.
Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- A proposal of an echocardiography-based pathway for the diagnosis and management of angina with no obstructive coronary arteries: a state-of-the-art review: Advancing Targeted Therapy and Prognosis Through Endotype Identification.European heart journal. Imaging methods and practice · 2026Review
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Authors and funding
7 authors.
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Abstract
Aims: To develop a ventilation navigator to provide controlled hyperventilation and to assess the feasibility to monitor hypocapnia and respiratory alkalosis in healthy subjects. Methods and results: We developed the Ventilation Navigator software using C++ and utilizing high-precision timers as an advanced platform for respiratory guidance and control, incorporating adjustable breathing rate, and tidal volume, a session timer for automatic cessation. Its graphical user interface is designed to deliver clear visual cues to the patient, facilitating controlled breathing. We assessed the utility of controlled hyperventilation in five healthy probands using end-tidal CO Conclusion: We developed a ventilation navigator application to deliver a controlled hyperventilation and assess its feasibility to monitor hypocapnia and respiratory alkalosis in healthy subjects. We are proposing this controlled physiological test to be implemented in the routine diagnostic workup to investigate coronary vasoreactivity in patients having angina with non-occlusive coronary artery disease after it has been validated in patients.
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