Evidence map›Paper›PMID 42311827›Full record

ArticleCase reports in surgery2026

Synchronous Ectopic Adrenal Rhabdomyosarcoma and Ipsilateral Cystic Nephroma Revealing a Diagnosis of DICER1-Related Tumor Predisposition: A Case Report.

Alejandro O Chara, Vikas S Gupta, Jiancong Liang, Scott C Borinstein, Daniel J Benedetti, Julia Shelton

Abstract read
In one paragraph

Article in Case reports in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alejandro O CharaDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA, vanderbilt.edu.ORCID https://orcid.org/0009-0009-0408-0830
Vikas S GuptaDepartment of Pediatric Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA, vanderbilt.edu.ORCID https://orcid.org/0000-0002-4625-7413
Jiancong LiangDepartment of Pediatrics, Division of Pediatric Pathology, Vanderbilt University Medical Center, Nashville, Tennessee, USA, vanderbilt.edu.ORCID https://orcid.org/0000-0002-7215-4346
Scott C BorinsteinDepartment of Pediatrics, Division of Pediatric Hematology/Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA, vanderbilt.edu.ORCID https://orcid.org/0000-0002-1721-1520
Daniel J BenedettiDepartment of Pediatrics, Division of Pediatric Hematology/Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA, vanderbilt.edu.ORCID https://orcid.org/0000-0003-1524-3518
Julia SheltonDepartment of Pediatric Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA, vanderbilt.edu.ORCID https://orcid.org/0000-0003-4038-9412

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DICER1-related tumor predisposition (DRTP) results from loss-of-function germline variants that predispose patients to numerous benign and malignant tumors. Cystic nephromas are among the most common neoplasms in patients with DRTP; however, there are no reports of rhabdomyosarcoma from adrenal tissue in children with DRTP. We present a case of a 30-month-old child with simultaneous cystic nephroma and rhabdomyosarcoma from ectopic adrenal tissue. He initially presented with chronic abdominal pain and poor weight gain. CT imaging demonstrated a large mass extending from the left kidney as well as an adjacent smaller mass in the retroperitoneum. Routine laboratory tests and tumor markers were unremarkable. He underwent an open left radical nephroureterectomy with excision of the midline retroperitoneal mass and lymph node dissection of the retrocaval and paraaortic basins. Pathologic examination revealed the larger mass to be a cystic nephroma, while the smaller mass was found to be embryonal rhabdomyosarcoma arising from ectopic adrenal tissue. Genetic testing of the rhabdomyosarcoma revealed a pathogenic c.4102dup (p.R1368fs) germline frameshift variant and a second c.5425G > A (p.G1809R) somatic missense variant in

Identifiers

PMID42311827
PMCPMC13269644

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