ArticleCureus2026
Suspected Neostigmine-Associated Bronchospasm Complicated by Pulmonary Edema During General Anesthesia: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Neostigmine inhibits cholinesterase activity and increases acetylcholine at the neuromuscular junction. Neostigmine is thus administered as an antagonist for non-depolarizing muscle relaxants during general anesthesia. However, neostigmine-induced pulmonary edema is extremely rare, making its diagnosis and appropriate treatment in the perioperative period challenging for anesthesiologists. A middle-aged obese woman underwent surgery for ptosis under general anesthesia because she was allergic to local anesthetics. At the end of surgery, she developed severe hypoxia (peripheral oxygen saturation (SpO
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