Evidence map›Paper›PMID 42311718›Full record

ArticleCureus2026

Marked Improvement of Chronic Motor and Phonic Tics With Cariprazine in an Adult With Tourette Syndrome With Comorbid Bipolar Disorder: A Case Report.

Gavin L Feinberg, George Burton, Jennifer J Hawkins, Jorge L Juncos

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gavin L FeinbergNeurology, Juncos Neuro Consulting, Cumming, USA.
George BurtonNeurology, Juncos Neuro Consulting, Cumming, USA.
Jennifer J HawkinsCounseling, Hawkins Counseling, Cumming, USA.
Jorge L JuncosNeurology, Juncos Neuro Consulting, Cumming, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tourette syndrome (TS) is a neuropsychiatric disorder characterized by motor and phonic tics, often complicated by comorbid conditions and treatment-related adverse effects. We report a 61-year-old male with long-standing TS and comorbid bipolar disorder who experienced persistent, functionally impairing tics despite multiple prior therapies. Following initiation and titration of cariprazine, the patient demonstrated marked and sustained improvement in tic severity over approximately two years, with good tolerability and stable mood symptoms. This case highlights a potential role for cariprazine in the management of tic disorders in patients with complex neuropsychiatric comorbidities.

Indexed as

bipolar disordercariprazinechronic motor ticschronic phonic ticsdopamine partial agonisttic disordertourette syndrome

Identifiers

PMID42311718
PMCPMC13271021

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.