ArticleCureus2026
Throwing Fracture of the Humerus in an Adolescent Patient Exposed to Isotretinoin: A Case Report of Successful Nonoperative Management.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Throwing fractures of the humerus are uncommon and typically occur in deconditioned adults. When they occur in adolescents, investigation into potential secondary causes is paramount. Medication history may provide insight into potential secondary causes of humerus fracture and should be investigated. While it is unclear whether isotretinoin plays a clinically significant role in fracture risk in humans, it has been associated with alterations in bone metabolism and should remain a topic of further study. Nonoperative management with a functional brace continues to be a mainstay of treatment in the absence of surgical indications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.