Evidence map›Paper›PMID 42311377›Full record

ReviewFrontiers in microbiology2026

Biodiversity and emerging infectious threats: the microbial dark matter of Southwest China.

Nan Guo, Zhiguo Liu, Zhenjun Li, Jianguo Xu

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nan GuoResearch Center for Reverse Microbial Etiology, Workstation of Academician, Shanxi Medical University, Taiyuan, China.
Zhiguo LiuState Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhenjun LiResearch Center for Reverse Microbial Etiology, Workstation of Academician, Shanxi Medical University, Taiyuan, China.
Jianguo XuResearch Center for Reverse Microbial Etiology, Workstation of Academician, Shanxi Medical University, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Southwest China is a global biodiversity hotspot, and its complex and diverse ecosystems harbor vast amounts of "microbial dark matter." This paper systematically examines the distribution characteristics of microbial dark matter in hosts such as arthropods, mammals, and birds, as well as in environments including soil, hot springs, and high-altitude lakes, with a particular focus on the cross-species transmissibility and pathogenic potential of emerging pathogens. Research indicates that new microbial species in the Southwest exhibit significant geographic concentration and host specificity: Yunnan Province is a core hotspot, while the Tibet Autonomous Region contributes a wealth of microbial resources due to its extreme environments, with arthropods and mammals accounting for the highest proportion of novel species. Regarding public health risks, eight novel pathogens with evidence of human infection have been identified, spanning the three major groups of viruses, bacteria, and parasites. The cross-species transmission potential of some pathogens (such as DPRV rhabdovirus, PPV arenaviridae, Luxi hantavirus, Banna virus and a novel

Indexed as

cross-species transmissionmicrobial dark matternovel pathogensSouthwest Chinazoonotic diseases

Identifiers

PMID42311377
PMCPMC13268901

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.