ArticleBiomedical optics express2026
Compact dual-channel visible-light fluorescence endoscope for real-time molecular imaging: system design and validation in ectopic pregnancy tissue.
Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Intraoperative identification of early ectopic pregnancy tissue remains challenging because chorionic villi often exhibit low visual contrast from surrounding inflamed or hemorrhagic tissue under conventional white-light endoscopy. To address this limitation, we developed a compact dual-channel visible-light fluorescence endoscopic imaging system configured as a modular 10 mm rigid endoscopic platform compatible with standard 10 mm laparoscopic workflows for real-time dual-channel acquisition and fusion. The system integrates a narrow-band 490 nm LED excitation source with a customized long-pass dichroic beam-splitting module to simultaneously acquire targeted fluorescence at ∼515 nm and diffuse reflectance at 490 nm. The two image streams are synchronized and fused to provide real-time molecular-anatomical visualization. Using a FITC-labeled anti-
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