Trial reportCNS neuroscience & therapeutics2026
Alpha-tACS Improves Executive Function and Alpha Power Spectral Density in Patients With Post-Stroke Cognitive Impairment.
Trial report in CNS neuroscience & therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Global Trends and Research Hotspots of Interventions for Post-Stroke Cognitive Impairment: A Bibliometric Analysis from 2005 to 2025.Healthcare (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundThis study aims to evaluate the efficacy of alpha-frequency transcranial alternating current stimulation (alpha-tACS) in treating post-stroke cognitive impairment (PSCI) and its effects on electroencephalographic activity.
methodsForty PSCI patients were randomly assigned to receive either active alpha-tACS (10 Hz, 2 mA over bilateral DLPFC) or sham stimulation for 4 weeks, combined with standard therapy. Cognitive function was assessed using MoCA and TMT-A/B, complemented by resting-state EEG. ROC analysis was employed to evaluate alpha power spectral density (PSD).
resultsFollowing the 4-week intervention, the alpha-tACS group demonstrated significantly greater improvements in MoCA scores and TMT-A completion times compared to the sham group (p < 0.05). Alpha power spectral density (PSD) increases were significantly more pronounced in the alpha-tACS group across all electrodes. Additionally, this group exhibited significantly greater reductions in whole-brain DAR and DTABR values (p
conclusionAlpha-tACS effectively enhances alpha oscillations and improves executive functions in PSCI patients, supporting its potential as a promising neuromodulatory intervention for cognitive rehabilitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.