ArticlePorcine health management2026
A pantothenic acid deficiency outbreak causing mortality and neuromuscular disorders in newborn and nursery piglets.
Article in Porcine health management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present case report describes the clinical and pathological outcomes of an outbreak of piglet mortality and neuromuscular disorders in newborn and nursery piglets caused by vitamin B5 deficiency. CASE PRESENTATION: A farrow-to-wean 750 sow-farm in Spain experienced abortions and respiratory signs in sows related to swine influenza during the first week of February 2025. It was followed by an unusual high piglet mortality rate within the first week post-farrowing, reaching up to 65% and persisting for seven weeks. Piglets were born apparently healthy, and colostrum intake was considered normal. Nevertheless, on the second day of life, they started showing apathy, ataxia, and prostration, most of them usually dying spontaneously on the third day of life. At the same time, at least 14 recently weaned piglets exhibited similar clinical signs and subsequently died. However, sows were completely unaffected. Initial antibiotic treatments were ineffective. Seven piglets were subjected to a complete necropsy. Five showed the above-mentioned neurological signs and two were completely healthy, which served as non-affected control animals. No relevant gross lesions were found. Histopathologically, neuronal bodies from cervical, thoracic, and lumbar spinal cord had variable degrees of central chromatolysis, cytoplasmic vacuolation, and swelling, with displaced nuclei and occasional necrosis. Some of the sampled sciatic nerves had mild-to-intense axonal swelling and fragmentation. Microscopic lesions were absent in the two non-affected pigs. Pantothenic acid deficiency was presumptively diagnosed, and all newborn piglets were treated with a vitamin B complex. The condition did not re-appear after treatment.
conclusionsInsufficient pantothenic acid intake should be among the differential diagnoses of piglets with ataxia, muscle weakness and mortality. A fast diagnosis based on complete nervous system sampling is key to diagnose and counteract this condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.