ArticleBMC ophthalmology2026
Epithelial cell proliferation on anterior surface of intraocular lens after Descemet stripping automated endothelial keratoplasty (DSAEK) surgery: a case report.
Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe report a rare case of histopathologically confirmed epithelial cell proliferation on the anterior surface of an intraocular lens (IOL) following Descemet stripping automated endothelial keratoplasty (DSAEK). CASE PRESENTATION: A 61-year-old female with a history of multiple ocular surgeries, including phacoemulsification cataract extraction and DSAEK, was referred for progressive visual deterioration. Clinical examination revealed resistant deposits on the anterior surface of the posterior chamber IOL, confined to the pupillary zone. Despite repeated interventions-including Nd: YAG laser treatment and surgical polishing of the IOL surface-the opacities persisted, ultimately necessitating IOL explantation and histopathological analysis. Light microscopy confirmed epithelial cell proliferation on the IOL surface. Examination of the stained lens revealed a sheath of cellular imprints and ghost cells. Unlike previously reported cases of IOL opacification, von Kossa staining demonstrated no calcium phosphate deposits, suggesting a distinct pathological mechanism originating from epithelial cell proliferation, likely derived from the capsular bag.
conclusionsEpithelial cell proliferation should be considered in the differential diagnosis of unexplained, persistent IOL surface opacities following DSAEK. In this case, definitive diagnosis was established only through histopathological evaluation of the explanted lens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.