Evidence map›Paper›PMID 42310461›Full record

ArticleNature2026

Spatial distribution of the proteome in the human body and in cancers.

Liang Yue, Wenhao Jiang, Sainan Li, Meng Luo, Ning Fan, Xiaolu Zhan, Rui Sun, Honghan Cheng, Zhangzhi Xue, Tong Liu and 30 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

Liang Yue *Affiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.ORCID http://orcid.org/0000-0001-6478-7306
Wenhao Jiang *Affiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.ORCID http://orcid.org/0009-0000-9381-9848
Sainan Li *Affiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Meng Luo *Department of Anatomy, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Ning FanDepartment of Anatomy, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Xiaolu ZhanHarbin Medical University Cancer Hospital, Harbin, China.
Rui SunAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.ORCID http://orcid.org/0000-0002-8484-8089
Honghan ChengAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Zhangzhi XueAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Tong LiuHarbin Medical University Cancer Hospital, Harbin, China.ORCID http://orcid.org/0000-0001-9234-1328
Qianhe ZhouHarbin Medical University Cancer Hospital, Harbin, China.
Kexin ChenHarbin Medical University Cancer Hospital, Harbin, China.
Tian LuAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Fang GuoDepartment of Gynecology, Southern Medical University Shenzhen Hospital, Shenzhen, China.
Dongwei LiKey Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medical Sciences, Hainan Academy of Medical Sciences, Hainan Medical University, Haikou, China.
Weigang GeWestlake Omics (Hangzhou) Biotechnology, Hangzhou, China.
Zongxiang NieAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Mengge LyuAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Jun AAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Yingrui WangAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.ORCID http://orcid.org/0000-0001-5532-3454
Yingdan ChenWestlake Omics (Hangzhou) Biotechnology, Hangzhou, China.
Zhenhai FuWestlake Omics (Hangzhou) Biotechnology, Hangzhou, China.
Nan XiangAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Lu LiAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Fengchao YuDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-7695-3698
Guo Ci TeoDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
Alexey I NesvizhskiiDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-2806-7819
Meng WangGilbert S. Omenn Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0001-5672-1411
Michael P SnyderDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-0784-7987
Ben C CollinsSchool of Biological Sciences, Queen's University Belfast, Belfast, UK.ORCID http://orcid.org/0000-0003-0827-3495
Qi XiaoAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China.
Ruedi AebersoldInstitute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-9576-3267
Fei XuDepartment of Anatomy, College of Medical Sciences, South China University of Technology, Guangdong, China.
Hui YangDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-2865-5311
Sijia ZhangState Key Laboratory of Frigid Zone Cardiovascular Diseases, Laboratory of Cardiovascular Disease and Molecular Intervention, Harbin Medical University, Harbin, China.
Yi HanDepartment of Critical Care Medicine, Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Yi ZhuAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China. zhuyi@westlake.edu.cn.ORCID http://orcid.org/0000-0003-0429-0802
Yong JiState Key Laboratory of Frigid Zone Cardiovascular Diseases, Laboratory of Cardiovascular Disease and Molecular Intervention, Harbin Medical University, Harbin, China. yongji@hrbmu.edu.cn.ORCID http://orcid.org/0000-0003-2650-5747
Yan LiDepartment of Emergency and Critical Disease, Songjiang Research Institute, Shanghai Key Laboratory of Emotion and Affective Disorders, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ly316@126.com.ORCID http://orcid.org/0000-0002-5158-1816
Tiannan GuoAffiliated Hangzhou First People's Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, Westlake University, Hangzhou, China. guotiannan@westlake.edu.cn.ORCID http://orcid.org/0000-0003-3869-7651

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A detailed, spatially resolved quantitative map of the human proteome is essential for a deeper understanding of human biology and disease

Indexed as

NeoplasmsProteomeAdultAntineoplastic AgentsFemaleFetusHumansMass SpectrometryOrgan SpecificityProteomicsAntineoplastic AgentsProteome

Identifiers

PMID42310461
PMCPMC13442039

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.