Evidence map›Paper›PMID 42310452›Full record

ArticleNature2026

Confined migration induces non-lethal DNA damage in developing neurons.

Zhejing Zhang, Andres Canela, Junko Kurisu, Peilin Zou, Takumi Kawaue, Naotaka Nakazawa, Noriko Takeda, Mai Saeki, Masaki Utsunomiya, Merve Bilgic and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zhejing ZhangInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Andres CanelaGraduate School of Biostudies, Kyoto University, Kyoto, Japan.
Junko KurisuInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Peilin ZouInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Takumi KawaueInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Naotaka NakazawaInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan.ORCID http://orcid.org/0000-0002-8695-4344
Noriko TakedaInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Mai SaekiInstitute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.
Masaki UtsunomiyaInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Merve BilgicInstitute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.
Fumiyoshi IshidateInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Gianluca GrenciMechanobiology Institute, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0001-9313-6748
Takahiro FurutaDepartment of Systematic Anatomy and Neurobiology, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.ORCID http://orcid.org/0000-0002-8758-631X
Yusuke KishiInstitute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0003-2846-5400
Hiroyuki SasanumaDepartment of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mineko KengakuInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Kyoto, Japan. kengaku@icems.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0002-1666-3648

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migratory cells tend to have soft nuclei that deform and penetrate narrow spaces

Indexed as

Cell MovementDNA Breaks, Double-StrandedDNA DamageNeuronsAnimalsCerebellumDNA Ligase ATPDNA RepairDNA Topoisomerases, Type IIFemaleMaleMiceNuclear EnvelopeTranscription, GeneticDNA Ligase ATPDNA Topoisomerases, Type II

Identifiers

PMID42310452
PMCPMC13293896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.