Evidence map›Paper›PMID 42310444›Full record

ArticleNpj imaging2026

Complementary hyperpolarized

Ingeborg S Skre, Magnus Karlsson, Juan D Sánchez-Heredia, Vebjørn S Skre, Peter A Rasmussen, Mathilde H Lerche

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Npj imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ingeborg S SkreSection for Magnetic Resonance, Department of Health Technology, Technical University of Denmark, Kgs, Lyngby, Denmark.
Magnus KarlssonSection for Magnetic Resonance, Department of Health Technology, Technical University of Denmark, Kgs, Lyngby, Denmark.
Juan D Sánchez-HerediaTechnical University of Cartagena (UPCT), Cartagena, Spain.
Vebjørn S SkreDepartment of Electrical and Photonics Engineering, Technical University of Denmark, Kgs, Lyngby, Denmark.
Peter A RasmussenSection for Magnetic Resonance, Department of Health Technology, Technical University of Denmark, Kgs, Lyngby, Denmark.
Mathilde H LercheSection for Magnetic Resonance, Department of Health Technology, Technical University of Denmark, Kgs, Lyngby, Denmark. mhauler@dtu.dk.

Funding

Novo Nordisk Fonden 0080322Novo Nordisk Fonden 19OC0055825
6 · The paper itself

Abstract

Metabolic dysfunction and hepatocellular injury coexist in liver disease but remain difficult to disentangle non-invasively. Hyperpolarized magnetic resonance imaging (HP MRI) enables in vivo metabolic interrogation but has primarily been applied to rapid exchange pathways. Here we evaluate whether complementary hyperpolarized molecular probes provide pathway-specific information on hepatic injury and methyl-donor metabolism in a rat model of steatohepatitis induced by a methionine- and choline-deficient diet. Hyperpolarized [1,4-

Identifiers

PMID42310444
PMCPMC13282476

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.