Evidence map›Paper›PMID 42310422›Full record

ReviewNPJ precision oncology2026

Towards an ecosystem of clinical decision support tools for precision cancer medicine.

Sigve Nakken, Anders Edsjö, Janne Lehtiö, Vigdis Nygaard, Paul Roepman, Richard Rosenquist, Hege G Russnes, Albrecht Stenzinger, David Tamborero, Sen Zhao and 2 more

Abstract readReview
In one paragraph

Review in NPJ precision oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sigve NakkenDepartment of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway. sigven@ifi.uio.no.
Anders EdsjöDepartment of Clinical Genetics, Pathology and Molecular Diagnostics, Skåne University Hospital, Lund, Sweden.
Janne LehtiöDepartment of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden.
Vigdis NygaardDepartment of Pathology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Paul RoepmanHartwig Medical Foundation, Amsterdam, the Netherlands.
Richard RosenquistDepartment of Molecular Medicine and Surgery, Karolinska Institutet, and Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.
Hege G RussnesDepartment of Pathology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Albrecht StenzingerInstitute for Pathology, Heidelberg University Hospital, Heidelberg, Germany.
David TamboreroDepartment of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden.
Sen ZhaoDepartment of Pathology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
PCM4EU consortium
Eivind HovigDepartment of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

Funding

Norges Forskningsråd 262652
6 · The paper itself

Abstract

Molecular tumor boards are supported by clinical decision support system (CDSS) tools for the interpretation of complex molecular data towards personalized treatments. Current CDSS tools are genomics-focused and characterized by tight couplings between data ingestion, guideline-based reasoning logic and curated knowledgebases. Next-generation CDSS solutions should integrate multimodal data and learn from outcomes in an interoperable ecosystem, leveraging explainable, trustworthy output from AI models through rigorous clinical validation processes.

Identifiers

PMID42310422
PMCPMC13639056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.