ArticleInternational journal of obesity (2005)2026
Alcohol use disorders and related morbidity and mortality after sleeve gastrectomy and Roux-en-Y gastric bypass: a nation-wide registry study (the BAR-REGISTER).
Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Ethanol pharmacokinetics before and after sleeve gastrectomy and Roux-en-Y gastric bypass: a 3 year prospective study (the BAR-TRIAL).International journal of obesity (2005) · 2026Observational
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundBariatric surgery provides notable weight loss and metabolic benefits but may also increase the risk of alcohol use disorder (AUD). We investigated whether Roux-en-Y gastric bypass (RYGB) confers higher rates of AUD and related disorders than sleeve gastrectomy (SG) and examined associated morbidity and mortality.
methodsWe conducted a retrospective, population-based cohort study using data from the Norwegian Patient Registry and the Norwegian Prescription Database. A total of 17,800 patients underwent RYGB (n = 12,244) or SG (n = 5556) between 2008 and 2018. Patients with prior diagnoses related to alcohol or use of medications for AUD were excluded. Incidence rates (IR) for alcohol-related diagnoses were calculated per 1000 person-years; hazard ratios (HR) were derived comparing RYGB to SG. Morbidity was measured as number of specialized healthcare contacts, but also as number of prescriptions/defined daily doses in an exploratory model.
resultsMean postoperative follow-up was 5.7 years (RYGB) and 3.8 years (SG). By 31 December 2018, 576 patients (3.2%) had developed a new alcohol-related diagnosis - an incidence rate of 6.34 per 1000 person-years. The adjusted HR for such diagnoses was 1.69 (95% CI 1.33-2.13, p < 0.001) for patients undergoing RYGB compared to SG. Because mortality did not differ significantly between RYGB and SG, mortality was assessed for the cohort as a whole: patients with alcohol-related diagnoses had an adjusted HR for death of 2.08 (95% CI 1.40-3.08) relative to those without. They also recorded, on average, 5.5 additional contacts in specialist care.
conclusionsCompared with SG, RYGB was associated with a 69% higher risk of alcohol-related diagnoses. Further, given the elevated morbidity and mortality linked to these disorders, enhanced preoperative screening and long-term postoperative monitoring are warranted in modern bariatric practice.
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