Evidence map›Paper›PMID 42310386›Full record

Observational studyInternational journal of obesity (2005)2026

Ethanol pharmacokinetics before and after sleeve gastrectomy and Roux-en-Y gastric bypass: a 3 year prospective study (the BAR-TRIAL).

Magnus Strømmen, Ola Dale, Christian Klöckner, Ida Tylleskär

Registry-linked trialAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01840020 (Changes in Bioavailability of Ethanol Following Bariatric Surgery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01840020 completednot on this map

Changes in Bioavailability of Ethanol Following Bariatric Surgery

TypeobservationalSponsorNorwegian University of Science and TechnologyRan2013 to 2020Enrolled33ConditionsObesity, MorbidArmsGastric bypass, gastric sleeve
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Magnus StrømmenCentre for Obesity Research, Clinic of Surgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. magnus.strommen@stolav.no.ORCID http://orcid.org/0000-0002-4686-0263
Ola DaleDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.ORCID http://orcid.org/0000-0001-9493-2658
Christian KlöcknerCentre for Obesity Research, Clinic of Surgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.ORCID http://orcid.org/0000-0003-4510-1748
Ida TylleskärDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.ORCID http://orcid.org/0000-0002-3220-1961

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare ethanol pharmacokinetics before and after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) over a three-year period.

methodsThis was a prospective, longitudinal, non-randomized controlled study at St. Olavs Hospital, Trondheim, including 33 adults without histories of alcohol use disorder (RYGB: n = 14; SG: n = 19). Participants underwent oral and intravenous ethanol challenge tests preoperatively and at 3, 12, and 36 months postoperatively. Primary outcomes included maximum plasma concentration (C

resultsThe ethanol uptake after both surgical procedures was bioequivalent for AUC

conclusionBoth RYGB and SG permanently altered ethanol pharmacokinetics, resulting in faster absorption, higher peak concentrations, and higher systemic exposure of alcohol. These changes, which were more pronounced after RYGB, may increase the risk of alcohol use disorders post-surgery. Awareness of the pharmacokinetic effects on RYGB and SG may be relevant for patient education, surgical decision-making, and postoperative monitoring. CLINICAL

trial registrationThis study was registered in ClinicalTrials.gov on May 15 2013. Identifier: NCT01840020.

Indexed as

EthanolGastrectomyGastric BypassObesity, MorbidAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesEthanol

Identifiers

PMID42310386
PMCPMC13391354

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.