Evidence map›Paper›PMID 42310384›Full record

ArticleScientific reports2026

Choroidal thickness on optical coherence tomography as a longitudinal predictor of visual outcomes in intermediate uveitis.

Suchitra Biswal, Pradeep Sagar, Marie D Just, Nicholas R Merten, Moritz Berger, Jan H Terheyden, Matthias Schmid, Frank G Holz, Robert P Finger, Maximilian W M Wintergerst

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Suchitra Biswal *Department of Medical Retina and Uvea, Sankara Eye Hospital, Shivamogga, India.
Pradeep Sagar *Department of Medical Retina and Uvea, Sankara Eye Hospital, Shivamogga, India.
Marie D Just *Department of Ophthalmology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Nicholas R MertenDepartment of Ophthalmology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Moritz BergerCore Facility Biostatistics, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.
Jan H TerheydenDepartment of Ophthalmology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Matthias SchmidDepartment of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Frank G HolzDepartment of Ophthalmology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Robert P FingerDepartment of Ophthalmology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Maximilian W M WintergerstDepartment of Ophthalmology, University Hospital Bonn, University of Bonn, Bonn, Germany. maximilian.wintergerst@ukbonn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess longitudinal changes in subfoveal choroidal thickness (SFCT) and mean choroidal thickness (MCT) in intermediate uveitis, eyes with at least one follow-up visit were included. These eyes were stratified into clinically worsened, stable, or improved based on changes in clinical parameters including Standardization of Uveitis Nomenclature (SUN) classification, to evaluate their prognostic value for future best-corrected visual acuity (BCVA) and central retinal thickness (CRT). Spectral domain optical coherence tomography (Heidelberg Engineering, Germany) was used to image the central macula. SFCT, MCT, and CRT were measured manually within the central 1 mm. Mixed-effects regression analysis controlling for age and sex was used to evaluate the prognostic value of SFCT and MCT regarding future BCVA and CRT. A total of 91 eyes from 52 patients were included in the analysis. While 12 eyes worsened, 62 remained stable, and 17 improved. Choroidal thickness remained stable over time, with no significant differences in SFCT or MCT change between clinical groups (p > 0.5 for all). When controlling for age and sex, both the baseline SFCT (estimate = -0.35 × 10

Indexed as

ChoroidTomography, Optical CoherenceUveitis, IntermediateVisual AcuityAdultFemaleHumansMaleMiddle AgedPrognosisIntermediate uveitisLongitudinalOCTOptical coherence tomography

Identifiers

PMID42310384
PMCPMC13276247

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