ArticleScientific reports2026
Early cancer biomarker detection using a prism-based multi-resonant Ag/BaTiO₃/BP plasmonic sensor.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Early and precise detection of cancer biomarkers with a ultra low concentration is a critical issue in clinical diagnostics mainly because of limited sensitivity, low selectivity as well as variable workability of the conventional surface plasmon resonance (SPR) biosensors. In order to deal with these drawbacks, this paper suggests a new prism-based, multi-resonant SPR biosensor with an Ag/BaTiO3/Black Phosphorus (BP) heterostructure. The goal is to improve field confinement, responsive refractive index and multiplexing capability to detected cancer biomarkers at an early-stage. The transfer matrix method was used to model the biosensor design and this was confirmed by finite element-based electromagnetic finite element simulations. The main plasmonic coating is Silver, BaTiO3 is a high-permittivity dielectric spacer to stabilize field coupling and the anisotropic BP is the active sensing material. Results of the simulation show an angular sensitivity of 412.14°/RIU and a figure of merit (FOM) of 352.26 RIU
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