Evidence map›Paper›PMID 42310223›Full record

ArticleCardiovascular and interventional radiology2026

Hepatic Encephalopathy after Transjugular Intrahepatic Portosystemic Shunt Using Dedicated versus Generic Stent-Grafts in Cirrhotic Patients.

Chengjian Wu, Zhaoyan Gao, Yi Shen, Guofeng Liu, Xiaoze Wang, Xuefeng Luo

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Chengjian WuDepartment of Gastroenterology and Hepatology, Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, West China Hospital, Sichuan University, 37 Guoxue Lane, Chengdu, 610041, Sichuan, China.
Zhaoyan GaoWest China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Yi ShenDepartment of Gastroenterology and Hepatology, Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, West China Hospital, Sichuan University, 37 Guoxue Lane, Chengdu, 610041, Sichuan, China.
Guofeng LiuDepartment of Gastroenterology and Hepatology, Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, West China Hospital, Sichuan University, 37 Guoxue Lane, Chengdu, 610041, Sichuan, China.
Xiaoze WangDepartment of Gastroenterology and Hepatology, Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, West China Hospital, Sichuan University, 37 Guoxue Lane, Chengdu, 610041, Sichuan, China.
Xuefeng LuoDepartment of Gastroenterology and Hepatology, Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, West China Hospital, Sichuan University, 37 Guoxue Lane, Chengdu, 610041, Sichuan, China. luo_xuefeng@wchscu.cn.ORCID http://orcid.org/0000-0002-3992-5866

Funding

National Natural Science Foundation of China 82470640West China Hospital, Sichuan University ZYGD23031
6 · The paper itself

Abstract

purposeTo compare the incidence of hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunt (TIPS) using two types of expanded polytetrafluoroethylene (ePTFE)-covered stents: dedicated stent-graft (DSG; Viatorr) versus generic stent-graft (GSG; Fluency) in patients with cirrhosis. MATERIALS AND

methodsWe conducted a retrospective analysis of cirrhotic patients who underwent TIPS using DSGs or GSGs between January 2012 and March 2024. Propensity score matching (PSM) was used to adjust for baseline differences between the two groups. The primary outcome was overt hepatic encephalopathy (OHE). Secondary outcomes included shunt dysfunction and transplant-free overall survival (TF-OS).

resultsAfter matching, 320 patients were included in each group. The cumulative incidence of OHE at 1, 2, and 3 years was lower in the DSG group than in the GSG group (16.1%, 21.9%, and 26.3% vs. 26.6%, 31.3%, and 33.7%; p = 0.013). After adjustment for confounders, DSGs were independently associated with a lower risk of OHE (subdistribution hazard ratio [sHR], 0.68; 95% CI, 0.51-0.91). Shunt dysfunction was also less frequent in the DSG group (2.9%, 5.2%, and 6.8% vs. 9.8%, 18.2%, and 23.7%; p < 0.001), with DSGs independently associated with a reduced risk (sHR, 0.29; 95% CI, 0.18-0.48). TF-OS did not differ significantly between the DSG and GSG groups (88.8%, 82.5%, and 76.8% vs. 90.3%, 83.1%, and 76.1%; p = 0.979).

conclusionsDSGs were associated with a lower risk of OHE and improved shunt patency compared with GSGs, supporting their preferential use in TIPS creation.

Indexed as

Hepatic EncephalopathyLiver CirrhosisPortasystemic Shunt, Transjugular IntrahepaticPostoperative ComplicationsStentsAgedFemaleHumansIncidenceMaleMiddle AgedPolytetrafluoroethylenePropensity ScoreProsthesis DesignRetrospective StudiesPolytetrafluoroethyleneDedicated stent-graftGeneric stent-graftHepatic encephalopathyShunt patencyTransjugular intrahepatic portosystemic shunt

Identifiers

PMID42310223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.