Evidence map›Paper›PMID 42310137›Full record

ArticleNature ecology & evolution2026

Rewiring of two conserved signalling hubs into one axis underlies convergent female-specific wing regression in insects.

Mingtao Liao, Xinyi Chen, Dong Zhao, Dongwei Yuan, Danyan Huang, Ziyu Yan, Liangqiong Huang, Jiaxin Ni, Qing Ma, Yufeng Pan and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature ecology & evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mingtao Liao *Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China.
Xinyi Chen *Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China.
Dong Zhao *State Key Laboratory of Gene Function and Modulation Research, School of Life Sciences, Peking University, Beijing, China.ORCID http://orcid.org/0000-0002-9255-9156
Dongwei Yuan *Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China.
Danyan HuangGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China.
Ziyu YanGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China.
Liangqiong HuangGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China.
Jiaxin NiState Key Laboratory of Gene Function and Modulation Research, School of Life Sciences, Peking University, Beijing, China.
Qing MaShenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Yufeng PanKey Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing, China.ORCID http://orcid.org/0000-0002-1535-9716
Yonggang HuState Key Laboratory of Resource Insects, Institute of Sericulture and Systems Biology, Southwest University, Chongqing, China.ORCID http://orcid.org/0000-0002-3438-7296
Armin P MoczekDepartment of Biology, Indiana University, Bloomington, IN, USA.
Wei ZhangState Key Laboratory of Gene Function and Modulation Research, School of Life Sciences, Peking University, Beijing, China. weizhangvv@pku.edu.cn.ORCID http://orcid.org/0000-0002-6644-7046
Chonghua RenGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China. renchonghua111@m.scnu.edu.cn.ORCID http://orcid.org/0000-0001-8221-0957
Sheng LiGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, China. lisheng@scnu.edu.cn.ORCID http://orcid.org/0000-0002-4217-2367

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32220103003National Natural Science Foundation of China (National Science Foundation of China) 32325009National Natural Science Foundation of China (National Science Foundation of China) 32370439National Natural Science Foundation of China (National Science Foundation of China) 32470542National Natural Science Foundation of China (National Science Foundation of China) 32530014
6 · The paper itself

Abstract

Sexual dimorphism represents a striking dimension of morphological diversity both within and across taxa. Female-specific wing regression (FSWR) is common in insects, but the mechanisms underlying this regression remain largely unknown. Here we show that FSWR is widespread among Pterygota insects, including cockroaches, where it contributes to ecological adaptation. We reveal that FSWR regulation involves sex-specific isoforms of DSX, a master regulator in the insect sex differentiation pathway, which oppositely regulate the expression of E93, the insect metamorphosis-controlling 'adult factor', during wing development. Mechanistically, DSX

Identifiers

PMID42310137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.