Evidence map›Paper›PMID 42310089›Full record

ArticleAesthetic plastic surgery2026

Modified Surgical Technique Combined with Radiation Therapy for Keloid Management.

Xueqing Wang, Kai Xie, Yilei Wu, Zhiqiang Zhang, Zhaojun Yuan, Jianke Li, Nan Cao, Xuan Guo, Honglei Wang, Zhaohua Bi and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xueqing Wang *Department of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Kai Xie *Department of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Yilei Wu *Department of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Zhiqiang ZhangDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Zhaojun YuanDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Jianke LiDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Nan CaoDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Xuan GuoDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Honglei WangDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Zhaohua BiDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Weixing XieDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Xiuhuan WangDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Guangliang ZhangDepartment of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China. zhguliang2006@163.com.ORCID http://orcid.org/0000-0003-3828-3301

Funding

Shandong Provincial Clinical Research Center for Dermatovenerology and the Medical health science and technology project of Shandong province Grant No. 202320001137Taishan Scholar Project Special Fund No. tsqn202312371
6 · The paper itself

Abstract

backgroundKeloids are skin proliferative lesions with tumor-like characteristics. Their treatment is challenging due to their high recurrence rate. The most effective treatment against keloids is surgical excision with radiotherapy. However, the recurrence rate remains high.

methodsIn this study, we modified the surgical technique by reducing the tension of an area three times larger than the residual wound area. We treated 89 patients using the modified surgical excision procedure with radiotherapy, and we assessed the appearance of the scar using the Vancouver scar scale (VSS) score.

resultsThe follow-up times ranged from 12 to 28 months with an average of 16.4 months. During the follow-up period, local recurrences were observed in 13 cases (14.6%). The mean VSS score decreased significantly after treatment (P < 0.001) indicating an improvement in the cosmetic appearance of scars.

conclusionThe modified surgical technique combined with radiation therapy may be an effective method for treating keloids. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors  www.springer.com/00266 .

Indexed as

KeloidAdolescentAdultCohort StudiesCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk AssessmentTreatment OutcomeWound HealingYoung AdultKeloidsRadiotherapyRecurrence rateSurgical excision

Identifiers

PMID42310089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.