Evidence map›Paper›PMID 42310055›Full record

Trial reportScientific reports2026

Evaluation of the alkaline water effect on the salivary bacteria of children: preliminary randomized trial.

Inas Karawia, Mohamed Ashraf Hall, Mona Abdelaziz Elbayoumi, Osama Safwat Mohamed

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Inas KarawiaDental Public Health and Preventive Dentistry, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt. inas.karawia@pua.edu.eg.ORCID https://orcid.org/0009-0000-8465-5685
Mohamed Ashraf HallAlexandria Dental Research Center, Ministry of Health and Population, Alexandria, Egypt.ORCID http://orcid.org/0000-0001-9452-4232
Mona Abdelaziz ElbayoumiDental Laboratories Technology, Faculty of Applied Health Science, Masr University for Science and Technology, Giza, Egypt.
Osama Safwat MohamedDental Laboratory Technology Department, Faculty of Health Sciences at Borg El Arab Technological University, Alexandria, Egypt.ORCID http://orcid.org/0000-0002-8745-6179

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental caries is a major public health concern among children, with Streptococcus species, particularly Streptococcus mutans, playing a key role in its development. This study aimed to compare the effect of alkaline water, chlorhexidine mouthwash, and tap water on the salivary Streptococcus count in children aged 10-12 years. A single-blinded preliminary clinical study was conducted on 60 healthy children aged 10-12 years. Three groups of participants were randomly assigned: one group used alkaline water, another group used mouthwash containing 0.12% chlorhexidine, and the third group used tap water as a control. Participants were followed for three weeks. Children with systemic diseases, orthodontic appliances, or recent use of antibiotics or corticosteroids were excluded. Unstimulated saliva samples were collected at baseline and after the intervention. Salivary Streptococcus counts were determined using standard microbiological techniques. After 3 weeks, mean salivary Streptococcus mutans counts (CFU ×10

Indexed as

Dental CariesMouthwashesSalivaStreptococcus mutansWaterBacterial LoadChildChlorhexidineFemaleHumansMaleSingle-Blind MethodChlorhexidineMouthwashesWaterAlkaline waterChlorhexidineDental cariesMixed dentitionStreptococcus

Identifiers

PMID42310055
PMCPMC13276252

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.