ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026
Association between intrinsic capacity and dementia risk in older Mexicans.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Intrinsic capacity impairment and incident dementia across three population-based cohorts: a harmonized individual participant data analysis.The journal of nutrition, health & aging · 2026Article
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7 authors.
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Abstract
introductionHealthy aging reflects the maintenance of intrinsic capacity (IC) across five physical and mental domains. Although IC decline has been linked to frailty and mortality, evidence regarding its predictive value for dementia remains limited, particularly in low- and middle-income countries.
methodsData from 7263 adults aged ≥60 years without baseline dementia from the Mexican Health and Aging Study (2012-2015) were analyzed. IC was assessed across vitality, locomotor, sensory, cognitive, and psychological domains. Dementia was defined as impairment in two or more cognitive domains plus one or more limitation in instrumental activities of daily living.
resultsThe mean age of the study population was 68.92 ± 6.8 years and 55.4% were women. Dementia incidence over 3 years was 4.15%. Higher baseline IC scores were associated with lower odds of incident dementia (adjusted odds ratio [OR] = 0.62; 95% confidence interval [CI]: 0.41-0.94). DISCUSSION: Our findings support the role of IC as an early, multidimensional marker of cognitive vulnerability.
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