ArticleJournal of clinical periodontology2026
A Pilot Comparative Study of Multi-Contrast Dental MRI and CBCT: Clinical Correlates of Disease Status and Inflammatory Burden in Periodontitis.
Article in Journal of clinical periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
aimTo evaluate the reliability of multi-contrast dental MRI (dMRI) for periodontal lesion assessment in comparison to cone-beam computed tomography (CBCT). Associations between imaging findings and clinical indicators of periodontal inflammation (i.e., bleeding on probing [BOP], periodontal probing depth [PPD] and periodontal inflamed surface area [PISA]) were analysed to explore the potential of dMRI to reflect disease status and inflammatory burden. MATERIALS AND
methodsIn this prospective study, patients with severe periodontitis underwent clinical examination, CBCT and 3T dMRI. Site-level detectability of periodontal osseous defects and/or marrow signal changes at the six standard clinical probing sites per tooth, as well as tooth-level lesion volumetry, were evaluated across CBCT, T1-weighted (T1W), contrast-enhanced T1W and T2-weighted (T2W). Reliability (κ, ICC) and clinical-imaging associations (Kruskal-Wallis and mixed-effect models) were analysed.
resultsNineteen patients with severe periodontitis stages III and IV were included. Reliability of dMRI matched CBCT (site-level κ = 0.631-0.771; tooth-level ICC = 0.832-0.973). Increasing PPD and BOP raised lesion detectability and volumes across all modalities, with dMRI being consistently more sensitive than CBCT. T1W MRI showed lesions and bone loss similar to CBCT and was unaffected by BOP (p = 0.132) or PPD (p = 0.252). T2W MRI identified most lesions regardless of PPD and reflected high correlations with BOP (p < 0.05), PPD (p < 0.001) and PISA (p < 0.001).
conclusionsReliability of dMRI for lesion identification and quantification was comparable to that of CBCT. The presence of T2W marrow oedema at sites with a CBCT-normal periodontal ligament space and no radiographically detectable bone loss may represent a promising imaging marker for early periodontal disease recognition and assessment of inflammatory burden.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.