Evidence map›Paper›PMID 42309761›Full record

ReviewThe Journal of reproduction and development2026

Manipulating primordial germ cells from chicken and other bird species.

Marcel H Blank, Kennosuke Ichikawa, Mike J McGrew

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of reproduction and development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marcel H BlankCentre for Tropical Livestock Genetics and Health (CTLGH), The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Edinburgh EH25 9RG, UK.
Kennosuke IchikawaDivision of Translational Bioscience, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Edinburgh EH25 9RG, UK.
Mike J McGrewCentre for Tropical Livestock Genetics and Health (CTLGH), The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Edinburgh EH25 9RG, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embryonic germ cells are the lineage restricted precursors to the gametes of the adult animal. Embryonic germ cells from birds offer a cellular system for both the conservation and the genetic modification of avian species. Ongoing discoveries in germ cell self-renewal pathways are extending the number of bird species for which germ cells can be in vitro cultured. Parallelly, the improved development of surrogate host embryos to carry exogenous germ cells is fostering more efficient and 3R-supportive methods to regenerate avian species from this cellular material. The next decade should lead to exciting developments which will aid in both understanding germ cell biology and avian conservation efforts.

Indexed as

BirdsEmbryonic Germ CellsGerm CellsAnimalsChick EmbryoChickensAvianAvian conservationChickenGene editingGerm cell culturePrimordial germ cell

Identifiers

PMID42309761
PMCPMC13286688

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.