Evidence map›Paper›PMID 42309722›Full record

ReviewThe Journal of reproduction and development2026

Developing stem cell-based bovine embryos for in vitro breeding.

Zongliang Jiang

Abstract readReview
In one paragraph

Review in The Journal of reproduction and development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Zongliang JiangDepartment of Animal Sciences, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32610, USA.

Funding

DNA Methylation at N6-Adenine in Placental Trophoblast DevelopmentR01HD102533 · NICHD · UNIVERSITY OF FLORIDA · PI JIANG, ZONGLIANG, XIAO, ZHUO ANDREW · 2020 to 2024
$3.1M
NICHD NIH HHS R01 HD102533
6 · The paper itself

Abstract

The rapid emergence of stem cell-based embryo models, such as blastocyst-like structures, or blastoids, leverages the remarkable self-organizing capabilities of cultured stem cells to generate structured, multicellular assemblies that replicate specific aspects of embryogenesis. This breakthrough opens new frontiers for our understanding of the earliest steps of embryogenesis and creation of promising innovative ARTs aimed at enhancing reproductive efficiency in cattle. This review begins by summarizing the bovine pluripotent stem cells including embryo-derived stem cells and induced pluripotency. Then the current progresses in generating bovine stem cell-derived embryos, blastoids, are explored. Finally, the potential application of bovine blastoid technology for in vitro breeding, and the key challenges and future directions are discussed.

Indexed as

BreedingEmbryonic DevelopmentEmbryonic Stem CellsPluripotent Stem CellsAnimalsCattleEmbryo Culture TechniquesFertilization in VitroARTBlastoidBovineEmbryoIn vitro breedingStem cells

Identifiers

PMID42309722
PMCPMC13286729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.