ArticleThe Journal of reproduction and development2026
Effects of laminin-treated membrane culture inserts on the growth of bovine oocyte-granulosa cell complexes collected from early antral follicles.
Article in The Journal of reproduction and development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Growing bovine oocytes represent a potential source of embryos, but this has not been adopted in practice. Although several offspring were produced following a two-week culture period, further optimization of the culture system is required. In vivo, the outermost granulosa cell layer is in direct contact with the basement membrane (BM); however, this interaction is absent in cultured oocyte-granulosa cell complexes (OGCs). Since the BM is known to have regulatory roles, this study examined the effects of BM components on oocyte growth by treating membrane inserts with laminin, a major BM constituent, or with the laminin-containing protein mixture Matrigel
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