Evidence map›Paper›PMID 42309601›Full record

ArticleJournal, genetic engineering & biotechnology2026

Comparative evaluation of antioxidant, cytoprotective, and anti-arthritic activities of pomegranate peel powder and coarse powdered date seeds: implications for functional nutrition.

Madyha H Mahmoud, Abdulrahman A Alsayegh, Nahla Kambal, Asrar Alsaeedi, Boshra M Mozaffar, Eman Merghani A Mohammed, Ashwag H Alwadani, Halah Abdulrahman Hafiz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal, genetic engineering & biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bioactive Phenolics fromAntioxidants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Madyha H MahmoudDepartment of Medical Laboratory Technology, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia. Electronic address: mhmohmoud@jazanu.edu.sa.
Abdulrahman A AlsayeghDepartment of Clinical Nutrition, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia. Electronic address: aalsayegh@jazanu.edu.sa.
Nahla KambalDepartment of Clinical Nutrition, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia. Electronic address: nhmohammed@jazanu.edu.sa.
Asrar AlsaeediDepartment of Clinical Nutrition, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia. Electronic address: aalsaeedi@jazanu.edu.sa.
Boshra M MozaffarDepartment of Clinical Nutrition, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia. Electronic address: Bmozaffar@jazanu.edu.sa.
Eman Merghani A MohammedDepartment of Clinical Practice, College of Pharmacy, Jazan University, Saudi Arabia.
Ashwag H AlwadaniDepartment of Clinical Nutrition, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia. Electronic address: Ashwagalwadani@jazanu.edu.sa.
Halah Abdulrahman HafizDepartment of Clinical Nutrition, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia. Electronic address: hahafiz@uqu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Agro-industrial byproducts are recognized as sustainable sources of bioactive compounds with potential applications in functional foods. Pomegranate peel and coarse powdered date seeds are among the most abundant fruit processing residues, yet remain underutilized despite their rich in polyphenols, organic acids and other phytochemicals composition. This study aimed to comparatively evaluate the antioxidant, cytoprotective, acetylcholinesterase inhibitory, and anti-arthritic activities of pomegranate peel powder (PPP) and coarse powdered date seeds (CPDS) using a panel of in vitro assays. Antioxidant capacity was assessed by DPPH radical scavenging and reducing power methods, while cytoprotective activity was evaluated using erythrocyte membrane stabilization and protective against oxidative DNA damage methods. Anti-arthritic potential was determined using protein denaturation and proteinase inhibition methods, and acetylcholinesterase inhibitory activity was also examined. PPP exhibited significantly higher activity compared to CPDS across most assays. PPP demonstrated stronger DPPH radical scavenging activity (IC

Indexed as

Agro-waste valorizationAntioxidant activityClinical nutritionCoarse powderedCytoprotectionDate seedsFunctional foodsPomegranate peel

Identifiers

PMID42309601
PMCPMC13156632

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.