Evidence map›Paper›PMID 42309444›Full record

ReviewUrology2026

Management of Xanthogranulomatous Pyelonephritis: A Review of Current Evidence and Treatment Strategies and a Proposed Clinical Management Algorithm.

Justin P Mehr, Daniel D Joyce, Jennifer B Gordetsky, Sam S Chang

Abstract readReview
In one paragraph

Review in Urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Justin P MehrDepartment of Urology, Vanderbilt University Medical Center, Nashville, TN.
Daniel D JoyceDepartment of Urology, Vanderbilt University Medical Center, Nashville, TN.
Jennifer B GordetskyDepartment of Urology, Vanderbilt University Medical Center, Nashville, TN; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN.
Sam S ChangDepartment of Urology, Vanderbilt University Medical Center, Nashville, TN. Electronic address: sam.chang@vumc.org.

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

Xanthogranulomatous pyelonephritis is an uncommon destructive inflammatory process of the renal parenchyma associated with urinary tract obstruction and infection. Preoperative diagnosis remains challenging with correct identification in less than half of cases. Management paradigms include immediate surgical intervention or staged approaches that emphasize preoperative optimization and percutaneous drainage. Radical nephrectomy remains the de facto definitive treatment though critical evidence gaps underscore the need for more rigorous study to guide management.

Indexed as

AlgorithmsPyelonephritis, XanthogranulomatousDrainageHumansNephrectomy

Identifiers

PMID42309444
PMCPMC13573023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.