Evidence map›Paper›PMID 42309389›Full record

ArticleThe ocular surface2026

Impact of the loss of tenascin X on tissue architecture and wound healing of the murine corneal stroma.

Takayoshi Sumioka, Hiroki Iwanishi, James V Jester, Rohan Joshi, Samantha Bradford, Shingo Yasuda, Masayasu Miyajima, Yuka Okada, Ken-Ichi Matsumoto, Shizuya Saika

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The ocular surface, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takayoshi SumiokaDepartment of Ophthalmology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-0012, Japan. Electronic address: sumioka@wakayama-med.ac.jp.
Hiroki IwanishiDepartment of Ophthalmology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-0012, Japan.
James V JesterGavin Herbert Eye Institute, University of California Irvine, 843 Health Science Road, Irvine, CA, 92697, USA.
Rohan JoshiGavin Herbert Eye Institute, University of California Irvine, 843 Health Science Road, Irvine, CA, 92697, USA.
Samantha BradfordGavin Herbert Eye Institute, University of California Irvine, 843 Health Science Road, Irvine, CA, 92697, USA.
Shingo YasudaDepartment of Ophthalmology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-0012, Japan.
Masayasu MiyajimaDepartment of Ophthalmology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-0012, Japan.
Yuka OkadaDepartment of Ophthalmology, Wakayama Medical University Kihoku Hospital, 219 Myoji, Katsuragi, Ito, Wakayama, 649-7113, Japan.
Ken-Ichi MatsumotoDepartment of Biosignaling and Radioisotope Experiment, Interdisciplinary Center for Science Research, Head Office for Research and Academic Information, Shimane University, 89-1 Enya-cho, Izumo, 693-8501, Japan.
Shizuya SaikaDepartment of Ophthalmology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-0012, Japan.

Funding

ROLE OF TGFBETA IN CORNEAL STROMAL WOUND HEALINGR01EY007348 · NEI · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI JESTER, JAMES V · 1987 to 2010
$4.5M
NEI UCI Center Core Grant for Vision ResearchP30EY034070 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vladimir Jivkov Kefalov · 2022 to 2026
$3.7M
Non-linear Optical Collagen Cross-linking (NLO CXL) for Treatment of Keratoconus.R01EY024600 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI JESTER, JAMES V · 2014 to 2024
$3.1M
NEI NIH HHS P30 EY034070NEI NIH HHS R01 EY007348NEI NIH HHS R01 EY024600
6 · The paper itself

Abstract

We investigated the role of tenascin X in the maintenance and healing of the corneal stroma using a tenascin X-null (Tnxb

Indexed as

CollagenCorneaKnockoutMouseMyofibroblastStromaTenascin XWound healing

Identifiers

PMID42309389
PMCPMC13521555

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.