Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
23 authors.
Woncheol JungDepartment of Oncology Science, College of Medicine, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0002-5473-9463
Hassan AbushukairDepartment of Oncology Science, College of Medicine, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0002-0068-5201
Nikhil Y PatilDepartment of Pharmaceutical Sciences, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0002-7750-4405
Felix AmpaduDepartment of Pharmaceutical Sciences, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0002-7499-498X
Maryam FirouziDepartment of Pharmaceutical Sciences, University of Oklahoma Health Campus, Oklahoma City, OK, USA.
Iulia RusDepartment of Pharmaceutical Sciences, University of Oklahoma Health Campus, Oklahoma City, OK, USA.
Jinhyuk ChoiThe Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID 0000-0002-1490-0179
Sree Deepthi MuthukrishnanDepartment of Oncology Science, College of Medicine, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0003-2257-9140
Surendra ShuklaDepartment of Oncology Science, College of Medicine, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0003-4490-8013
Stefano TarantiniOklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0001-5627-1430
Anna CsiszarOklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0003-4842-6660
Kamiya MehlaDepartment of Oncology Science, College of Medicine, University of Oklahoma Health Campus, Oklahoma City, OK, USA.
Dongin KimDepartment of Pharmaceutical Sciences, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0003-2078-6138
Je-Hyun YoonDepartment of Oncology Science, College of Medicine, University of Oklahoma Health Campus, Oklahoma City, OK, USA.
Dowoon KimKorea Institute of Analytical Science and Technology, Seoul, Republic of Korea.ORCID 0009-0002-7969-8300
Juyang KimKorea Institute of Analytical Science and Technology, Seoul, Republic of Korea.ORCID 0000-0002-0552-9937
Jaehak JungKorea Institute of Analytical Science and Technology, Seoul, Republic of Korea.ORCID 0000-0003-1832-6490
Oxana KlementievaMedical Microspectroscopy Lab, Department of Experimental Medical Science, Faculty of Medicine, Lund University, Lund, Sweden.ORCID 0000-0003-1782-050X
Yatrik M ShahDepartment of Molecular and Integrative Physiology and Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-2487-4816
Eiji YoshiharaThe Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID 0000-0001-6324-6495
Pankaj K SinghDepartment of Oncology Science, College of Medicine, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0001-8903-0131
Aditya D JoshiDepartment of Pharmaceutical Sciences, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0002-5208-5144
Tae Gyu OhDepartment of Oncology Science, College of Medicine, University of Oklahoma Health Campus, Oklahoma City, OK, USA.ORCID 0000-0002-2756-3546
Funding
Texas A&M Center for Environmental Health Research (TiCER)P30ES029067 · NIEHS · TEXAS A&M UNIVERSITY · PI Weston W Porter · 2019 to 2026
$13.0M
Targeting Tumor-Stromal Metabolic Cross-Talk in Pancreatic CancerR01CA163649 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Pankaj Kumar Singh · 2012 to 2026
$5.4M
Targeting the Metabolic Basis of Cachexia in Pancreatic CancerR01CA210439 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI SINGH, PANKAJ KUMAR · 2017 to 2021
$2.6M
Novel Mechanism of aryl hydrocarbon receptor-mediated differential gene regulationR01DK122028 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Aditya D Joshi · 2019 to 2026
$2.3M
Molecular Basis of ME2-mediated Tumor Suppression in Pancreatic CancerR01CA270234 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Pankaj Kumar Singh · 2022 to 2026
$2.2M
Spatiotemporal regulation of human islet organogenesisR01DK136888 · NIDDK · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI Eiji Yoshihara · 2024 to 2026
Microplastics (MPs) are increasingly recognized as an urgent global health concern, with mounting evidence linking their bioaccumulation to chronic disease risks. The liver, as a central organ for metabolic homeostasis and detoxification, is particularly sensitive to sustained MP exposure. However, the mechanisms underlying hepatic responses to polyethylene (PE), the most prevalent yet relatively understudied plastic type, remain poorly defined. By performing combined bulk and spatial transcriptomic analyses, we observed that PE resulted in hepatic dysfunction in mice fed on standard or metabolic dysfunction-associated steatohepatitis (MASH)-inducing diets, driving both globally and spatially distinct transcriptional alterations, including a nuclear receptor (NR),
Indexed as
Annexin A2Chemical and Drug Induced Liver InjuryMicroplasticsPPAR alphaTranscriptomeAnimalsGene Expression ProfilingGene Expression RegulationLiverMaleMiceSignal TransductionSpatial TranscriptomicsAnnexin A2MicroplasticsPPAR alphaPpara protein, mouse
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Spatial transcriptome mapping identifies · full record | OpenQuestion