Evidence map›Paper›PMID 42307994›Full record

ArticleChembiochem : a European journal of chemical biology2026

Histidine Ethylation by Histidine Methyltransferases SETD3 and METTL9.

Jordi C J Hintzen, Zhimei Yu, Sadaf Ahmad, Xin Zhang, Yuan-Yuan Zhao, Hao Deng, Leonie Schütz, Marija Ram, Julia Z Kaminska, Jakub Drozak and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jordi C J HintzenDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.
Zhimei YuDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.
Sadaf AhmadDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.
Xin ZhangSchool of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian, P. R. China.
Yuan-Yuan ZhaoChemistry and Materials Science Faculty, Shandong Agricultural University, Tai'an, P. R. China.
Hao DengChemistry and Materials Science Faculty, Shandong Agricultural University, Tai'an, P. R. China.
Leonie SchützInstitute of Organic Chemistry, RWTH Aachen University, Aachen, Germany.
Marija RamDepartment of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Julia Z KaminskaDepartment of Metabolic Regulation, Faculty of Biology, University of Warsaw, Warsaw, Poland.
Jakub DrozakDepartment of Metabolic Regulation, Faculty of Biology, University of Warsaw, Warsaw, Poland.
Elmar WeinholdInstitute of Organic Chemistry, RWTH Aachen University, Aachen, Germany.
Hong GuoDepartment of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee, USA.
Andrea RentmeisterDepartment of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Ping QianSchool of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian, P. R. China.
Jasmin MecinovićDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.

Funding

DFG Grant RE2796/10-1FOR Grant 510974120Independent Research Fund Denmark Grant 10.46540/3105-00324BNational Science Centre, Poland Grant 2017/27/B/NZ1/00161Natural Science Foundation of China Grant 22177064Natural Science Foundation of Shandong Province Grant ZR2021MB050
6 · The paper itself

Abstract

AdoMet-dependent histidine methyltransferases catalyze regioselective methylation of histidine residues in proteins. N

Indexed as

HistidineHistone MethyltransferasesMethyltransferasesProtein MethyltransferasesBiocatalysisHumansMethylationHistidineHistone MethyltransferasesMethyltransferasesProtein MethyltransferasesSETD3 protein, humanbiochemistrychemistryhistidineimidazolemethylationregioselectivity

Identifiers

PMID42307994
PMCPMC13274687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.