Observational studyLung2026
Clinically Meaningful Differences for Cough-Specific Visual Analogue Scale in Chronic Cough: A Real-World Study.
Observational study in Lung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
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Corrections and comments
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Authors and funding
24 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCough-specific visual analogue scale (VAS) is widely used to assess cough severity and frequency; however, clinically meaningful thresholds for treatment response in chronic cough (CC) remain uncertain in routine practice.
objectivesTo determine minimum clinically important differences (MCIDs) for cough VAS severity and frequency using real-world data anchored to both objective cough frequency and patient-reported quality of life.
methodsIn this prospective observational study, 103 patients with CC were evaluated before and after standard treatment. Cough severity and frequency were assessed using 100-mm VAS, health-related quality of life using the Leicester Cough Questionnaire (LCQ), and 24-hour cough frequency (CoFr
resultsVAS severity and frequency showed moderate, statistically significant correlations with both LCQ and CoFr
conclusionsIn the present study, both ΔVAS of 24 mm and %ΔVAS of 60-65% reduction in cough VAS represented clinically meaningful improvement. Percentage-based MCIDs may complement absolute thresholds across a range of baseline severity, supporting the use of VAS in clinical practice and trials.
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