Evidence map›Paper›PMID 42307295›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2026

Sex differences in 1,114,625 varicose vein surgeries: an 18-year cross-sectional analysis of the Brazilian public health system.

Clara Sanches Bueno, Bruna Castelucci Bongiovanni, Nickolas Stabellini, Stephanye Santos de Paula, Júlia Freire Castanheira de Paiva Ferreira, Bruno Jeronimo Ponte, Felipe Soares Oliveira Portela, Marcelo Fiorelli Alexandrino da Silva, Marcelo Passos Teivelis, Nelson Wolosker

Abstract read
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Clara Sanches BuenoHospital Israelita Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0003-2622-4996
Bruna Castelucci BongiovanniHospital Israelita Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0009-1284-1361
Nickolas StabelliniUniversity Hospitals Seidman Cancer Center, Department of Hematology-Oncology - Cleveland (OH), United States.ORCID http://orcid.org/0000-0002-3135-7980
Stephanye Santos de PaulaFaculdade Israelita de Ciências da Saúde Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0006-3679-174X
Júlia Freire Castanheira de Paiva FerreiraHospital Israelita Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0006-3090-5902
Bruno Jeronimo PonteHospital Israelita Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0002-7272-7423
Felipe Soares Oliveira PortelaHospital Israelita Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0002-1720-2771
Marcelo Fiorelli Alexandrino da SilvaHospital Israelita Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0002-0714-5291
Marcelo Passos TeivelisHospital Israelita Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0002-3648-6773
Nelson WoloskerHospital Israelita Albert Einstein - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0003-1991-3507

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChronic venous disease is a highly prevalent condition with significant morbidity. Although there is a well-documented predominance of chronic venous disease among women, the differences in surgical treatment based on sex, especially in low- and middle-income countries, are not well understood. The aim of this study was to investigate these disparities within Brazil's public healthcare system.

methodsThis cross-sectional study analyzed all varicose vein surgeries (n=1,114,625) performed in the public sector from 2007 to 2024. Data were extracted from the national open database (Sistema de Informações HospitalaresDepartamento de Informática do Sistema Único de Saúde (Department of Informatics of the Unified Health System). We compared demographics, procedural and mortality rates, age at surgery, length of hospital stays, and patterns of travel for surgery between the sexes.

resultsWomen constituted most of the procedures (80.5%). Men underwent bilateral surgery at a significantly older median age than women (49 vs. 47 years, p<0.01). Men were more likely to travel between cities (38.89 vs. 37.22%, p<0.01), while women traveled more between states (0.35 vs. 0.39%, p<0.021). Mortality rates were low for both sexes, but higher for men (0.0197 vs. 0.0023%, p<0.01).

conclusionThis study reveals significant gender disparities in the surgical treatment of varicose veins in Brazil, extending beyond mere prevalence to include differences in the age at which intervention occurs and geographic access patterns. The findings suggest that biological factors alone cannot account for these disparities, highlighting that healthcare-seeking behaviors, mortality rates, and structural inequities also play a crucial role. Further qualitative research is needed to elucidate the underlying motivations for these differences and to guide the development of more equitable healthcare policies.

Indexed as

Healthcare DisparitiesVaricose VeinsAdultAgedBrazilCross-Sectional StudiesFemaleHumansMaleMiddle AgedSex DistributionSex Factors

Identifiers

PMID42307295
PMCPMC13268410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.