Evidence map›Paper›PMID 42307235›Full record

ArticlemSystems2026

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Dianshuang Zhou, Liwei Tang, Mengdie Ni, Wen Yang, Xiangming Wang, Ying Li, Zuobin Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dianshuang Zhou *Jiangsu Engineering Center for Precision Diagnosis and Treatment Research of Polygenic Diseases, Key Laboratory of Genetic Foundation and Clinical Application, Department of Genetics, Xuzhou Medical University, Xuzhou, China.ORCID 0000-0002-9205-4641
Liwei Tang *Jiangsu Engineering Center for Precision Diagnosis and Treatment Research of Polygenic Diseases, Key Laboratory of Genetic Foundation and Clinical Application, Department of Genetics, Xuzhou Medical University, Xuzhou, China.
Mengdie Ni *Jiangsu Engineering Center for Precision Diagnosis and Treatment Research of Polygenic Diseases, Key Laboratory of Genetic Foundation and Clinical Application, Department of Genetics, Xuzhou Medical University, Xuzhou, China.
Wen YangThe First People's Hospital of Lianyungang, Lianyungang, China.
Xiangming WangDepartment of Cell Biology, Laboratory for Clinical Medicine, School of Basic Medical Sciences, Capital Medical University, Beijing, China.ORCID 0000-0002-5111-0512
Ying LiMedical Technology College, Xuzhou Medical University, Xuzhou, China.ORCID 0000-0002-1293-6610
Zuobin ZhuJiangsu Engineering Center for Precision Diagnosis and Treatment Research of Polygenic Diseases, Key Laboratory of Genetic Foundation and Clinical Application, Department of Genetics, Xuzhou Medical University, Xuzhou, China.ORCID 0000-0003-1022-5943

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the gut microbiota is known to influence host metabolism, how specific bacterial genetic mutations modulate lipid metabolism remains unclear. In this study, we integrated IMPORTANCE: Our findings carry several potential implications: they not only reveal a novel pathway through which a bacterial mutant affects host lipid metabolism via phosphatidylglycerol-mediated inhibition of fatty acid biosynthesis but also underscore the potential of engineered microbial strains as precision probiotics for the treatment of lipid-associated disorders.

Indexed as

Caenorhabditis elegansEscherichia coliEscherichia coli ProteinsFatty AcidsLipid MetabolismPhosphatidylglycerolsAnimalsCaenorhabditis elegans ProteinsLipidomicsMutationCaenorhabditis elegans ProteinsEscherichia coli ProteinsFatty AcidsPhosphatidylglycerolsCaenorhabditis eleganslipidmutant E. coliphosphatidylglycerol

Identifiers

PMID42307235
PMCPMC13386898

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.