Evidence map›Paper›PMID 42306995›Full record

SynthesisJournal of surgical oncology2026

Oncologic Outcomes After Liver Transplantation for Unresectable Colorectal Liver Metastases: A Systematic Review and Meta-Analysis of Proportions.

Bernardo Fontel Pompeu, Lorrany Ramos Aguiar, Giuliana Daneluci Melillo, Laryssa Santana Nakabayashi, Gabriel Leal Barone, Lucas Monteiro Delgado, Claudia Theis, Leonardo de Melo Del Grande, Sérgio Mazzola Poli de Figueiredo, Fernanda Bellotti Formiga and 1 more

Abstract readSystematic ReviewMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bernardo Fontel PompeuDepartment of Surgery, Heliopolis Hospital, São Paulo, Brazil.ORCID https://orcid.org/0009-0009-2960-3810
Lorrany Ramos AguiarDepartment of Surgery, Heliopolis Hospital, São Paulo, Brazil.ORCID https://orcid.org/0009-0001-5265-2508
Giuliana Daneluci MelilloDepartment of Surgery, Heliopolis Hospital, São Paulo, Brazil.ORCID https://orcid.org/0009-0000-2844-4197
Laryssa Santana NakabayashiDepartment of Surgery, Heliopolis Hospital, São Paulo, Brazil.ORCID https://orcid.org/0009-0000-7536-7825
Gabriel Leal BaroneUniversity of São Caetano do Sul, USCS, São Caetano do Sul, Brazil.ORCID https://orcid.org/0009-0006-6086-4240
Lucas Monteiro DelgadoFederal University of Minas Gerais, Belo, Horizonte, Brazil.ORCID https://orcid.org/0009-0001-7687-3073
Claudia TheisUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID https://orcid.org/0000-0002-1303-298X
Leonardo de Melo Del GrandeDepartment of Surgery, Federal University of São Paulo, UNIFESP, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-7115-1218
Sérgio Mazzola Poli de FigueiredoUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID https://orcid.org/0000-0003-2986-8164
Fernanda Bellotti FormigaDepartment of Surgery, Heliopolis Hospital, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-7225-7145
Alexsander Kuroiwa BressanDepartment of Surgery, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-1286-3992

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplantation has emerged as a therapeutic option for highly selected patients with unresectable colorectal liver metastases (CRLM). This review evaluated oncologic and perioperative outcomes in 92 patients who underwent transplantation. One- and 3-year overall survival (OS) were 96.32% and 73.07%, respectively. Disease-free survival (DFS) was lower, with high rates of recurrence. Major complications occurred in 39.36%, and 90-day mortality was 1.03%. Further randomized studies are needed to better define the role of liver transplantation and optimize patient selection criteria.

Indexed as

Colorectal NeoplasmsLiver NeoplasmsLiver TransplantationDisease-Free SurvivalHumansNeoplasm Recurrence, LocalSurvival RateTreatment Outcomecolorectal liver metastasesliver transplantationmeta‐analysisrecurrencesurvival

Identifiers

PMID42306995
PMCPMC13532978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.