Evidence map›Paper›PMID 42306973›Full record

SynthesisPsychological medicine2026

Economic evaluations of preventive interventions for self-harm and suicide: a systematic review.

Long Khanh-Dao Le, Dai Quy Le, Phuong Hong Le, Eng Joo Tan, Amanda Neil, Karl Andriessen, Jane Pirkis, Cathrine Mihalopoulos, Lennart Reifels

Abstract readSystematic Review
In one paragraph

Synthesis in Psychological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Long Khanh-Dao LeHealth Economics Group, Monash University, Melbourne, Australia.ORCID 0000-0002-9442-6824
Dai Quy LeHealth Economics Group, Monash University, Melbourne, Australia.ORCID 0000-0002-4745-9738
Phuong Hong LeHealth Economics Group, Monash University, Melbourne, Australia.ORCID 0000-0001-7924-3635
Eng Joo TanHealth Economics Group, Monash University, Melbourne, Australia.ORCID 0000-0003-4449-4404
Amanda NeilMenzies Institute for Medical Research, https://ror.org/04yvxvx65University of Tasmania, Hobart, Australia.ORCID 0000-0002-1344-6672
Karl AndriessenCentre for Mental Health and Community Wellbeing, Melbourne School of Population and Global Health, https://ror.org/01ej9dk98University of Melbourne, Melbourne, Australia.ORCID 0000-0002-3107-1114
Jane PirkisCentre for Mental Health and Community Wellbeing, Melbourne School of Population and Global Health, https://ror.org/01ej9dk98University of Melbourne, Melbourne, Australia.
Cathrine MihalopoulosHealth Economics Group, Monash University, Melbourne, Australia.
Lennart ReifelsCentre for Mental Health and Community Wellbeing, Melbourne School of Population and Global Health, https://ror.org/01ej9dk98University of Melbourne, Melbourne, Australia.ORCID 0000-0001-7844-5163

Funding

Department of Health and Ageing, Australian Government
6 · The paper itself

Abstract

Self-harm and suicide are major public health concerns and leading causes of mortality worldwide, highlighting a pressing need for policymakers to identify and implement cost-effective interventions. This systematic review (PROSPERO registration #CRD42023460339) followed the PRISMA guidelines and aimed to synthesize the available cost-effectiveness evidence for the prevention of self-harm and suicide. Systematic searches were performed in MEDLINE, Embase, PsycINFO, CINAHL, Econlit, and ProQuest to identify full economic evaluations and return-on-investment studies on preventive interventions for self-harm and suicide published up to January 15, 2026. Methodological quality was assessed using Drummond's 10-item checklist, and findings were synthesized narratively. A total of 69 eligible studies evaluated 22 types of interventions: three universal, five selective, five indicated, and nine multi-level. Most studies were rated as high-quality (

Indexed as

Cost-Benefit AnalysisCost-Effectiveness AnalysisSelf-Injurious BehaviorSuicide PreventionHumansPsychotherapycost-effectivenesseconomic evaluationpreventionself-harmsuicidesystematic review

Identifiers

PMID42306973
PMCPMC13280699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.