Evidence map›Paper›PMID 42306936›Full record

ArticleTransboundary and emerging diseases2026

Emergence of Transferable Plasmid Coharboring mcr-1.1 and bla

Zizhu Lin, Weiqi Guo, Jiangang Hu, Zhiyang Wang, Beibei Zhang, Xinyu Wang, Haoheng Peng, Jingjing Qi, Mingxing Tian, Yanqing Bao and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transboundary and emerging diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Emergence of Transferable Plasmid Coharboring mcr-1.1 and blaTransboundary and emerging diseases · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zizhu LinShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Weiqi GuoShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Jiangang HuShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Zhiyang WangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Beibei ZhangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Xinyu WangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Haoheng PengShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Jingjing QiShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Mingxing TianShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Yanqing BaoShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Lei DengShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.
Xue BaiKey Laboratory of Special Animal Epidemic Disease, Ministry of Agriculture and Rural Affairs, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, 130112, China, caas.cn.ORCID https://orcid.org/0000-0002-9291-949X
Haihua LiTianjin Key Laboratory of Agricultural Animal Breeding and Healthy Husbandry, College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin, 300384, China, tjac.edu.cn.ORCID https://orcid.org/0000-0002-0148-9640
Shaohui WangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China, caas.cn.ORCID https://orcid.org/0000-0003-0170-3309

Funding

Agricultural Science and Technology Innovation Program CAAS-ASTIP-2026-SHVRICentral Public-interest Scientific Institution Basal Research Fund 2026JB13Central Public-interest Scientific Institution Basal Research Fund 2026JB17Central Public-interest Scientific Institution Basal Research Fund Y2026YC46Guangxi Key Research and Development Program AB23075145Guangxi Key Research and Development Program FN2600640636National Natural Science Foundation of China 32302881Shanghai Agricultural Science and Technology Innovation Project 2025-02-08-00-12-F00042
6 · The paper itself

Abstract

Multidrug-resistant (MDR) bacteria have reduced the effectiveness of antimicrobial agents and limited available treatment options in both human and animal settings. Antimicrobial resistance (AMR) in animal-derived Escherichia coli (E. coli) has become increasingly common, with many isolates showing resistance to multiple classes of antimicrobials. However, compared with other animal sources, resistance characteristics of E. coli from mink remain less well understood, particularly in terms of genomic features. In this study, we identified a MDR E. coli strain, EC0D1, isolated from the lung tissue of a farmed mink that succumbed to hemorrhagic pneumonia (HP) in China. Antimicrobial susceptibility testing indicated that EC0D1 exhibited resistance to β-lactams, fluoroquinolones, aminoglycosides, tetracyclines, and polymyxins but was sensitive to carbapenems and tigecycline. Whole genome sequencing showed that EC0D1 contains a single chromosome and eight plasmids. Among these, plasmid pEC0D1-3 coharbored bla

Indexed as

beta-LactamasesDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsMinkPlasmidsAnimalsAnti-Bacterial AgentsAnti-Bacterial Agentsbeta-lactamase CTX-M-55, E colibeta-LactamasesEscherichia coli ProteinsMCR-1 protein, E coliblaCTX-M−55Escherichia colimcr-1.1multidrug resistancewhole genome sequencing

Identifiers

PMID42306936
PMCPMC13273531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.