ArticleNucleic acids research2026
LiMeNEx: an interactive webserver on lipid biochemical gene-regulatory network.
Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Lipid metabolism represents an intricate landscape of biochemical reactions catalyzed by enzymes and regulated by transcription factors (TFs) to maintain metabolic homeostasis. Disruption of the enzymatic or transcriptional machinery is associated with lipid imbalance, contributing to diverse pathological conditions across tissues and the physiological system. However, existing pathway resources predominantly focus on metabolic map reactions but lack integration of upstream regulatory components, limiting system-level interrogation of lipid-associated mechanisms. We present LiMeNEx (Lipid Metabolic Network Explorer), an interactive webserver for exploration of lipid biochemical gene regulatory networks that link lipids, enzymes, and TFs. LiMeNEx integrates carefully curated 504 biochemical reactions across 22 lipid pathways, involving 330 enzymatic genes and 345 TFs mapped across 50 human tissues and 11 physiological systems. The three consols of LiMeNEx allow users to query lipids for visualization of lipid pathways and genes involved in lipid-enzyme reactions, and to explore tissue and systems-specific transcriptional regulators of target genes. LiMeNEx provides a holistic view of lipid metabolism with comprehensive documentation for intuitive navigation. By integrating metabolic and regulatory layers in a tissue-resolved framework, it enables hypothesis-driven system-level investigation of lipid metabolism and related disorders. LiMeNEx is freely available at https://limenex.raylab.iiitd.edu.in/.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.