ArticleJournal of thoracic disease2026
Tumor stage, squamous histology and male sex predict positive resection margins in non-small cell lung cancer patients undergoing anatomical resection-a retrospective study from a high-volume thoracic surgery unit.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The aim of the study is to identify perioperative predictors of positive resection margins in patients with non-small cell lung cancer (NSCLC) undergoing anatomical resections to improve perioperative risk stratification and ultimately, patient care. Methods: All patients with primary NSCLC admitted at the Bundeswehrkrankenhaus (Armed Forces Hospital) Ulm for anatomical resections between 01.01.2019 and 31.12.2024 were retrospectively included into the study. Based on resection margins, patients were categorized in two groups: Group 1 (with negative resection margins, R Results: Of 232 NSCLC patients [median age 69.00 (63.00, 75.00) years, 22% aged >75 years, and 2.2% with an Eastern Cooperative Oncology Group (ECOG) >2] who underwent anatomical resections, 107 (46.1%) female patients were included. While R Conclusions: T stage (pT >2), squamous histology and male sex predict positive resection margins in lung cancer patients undergoing anatomical resections. Consideration of these parameters could help in patients' stratification and care and thus, should be further evaluated in larger patients' cohorts.
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