ArticleJournal of thoracic disease2026
Clinical phenotypes of secondary spontaneous pneumothorax (SSP) in different underlying lung diseases: a retrospective study and literature review on the clinical heterogeneity in this single entity.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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7 authors.
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Abstract
Background: The clinical outcome of secondary spontaneous pneumothorax (SSP) was mostly evaluated in chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD) patients whereas data were limited in non-COPD/ILD-related pneumothorax. This study aimed to describe the clinical outcome of pneumothorax secondary to different pulmonary conditions. Methods: A retrospective observational study was conducted on SSP patients in a Hong Kong hospital. Clinical outcome of pneumothorax secondary to different underlying lung diseases including persistent air leak (PAL), 2-year post-discharge pneumothorax recurrence and all-cause mortality were evaluated. Logistic regression and cox regression analysis were applied for covariates adjustment. Results: Of the 223 SSP patients enrolled, 32 (14.3%) had acute chest infection and 191 (85.7%) had chronic lung diseases. The acute chest infection group had higher risk of PAL >14 days (40.6% Conclusions: Our study demonstrated heterogeneous clinical phenotypes among different lung diseases with poorer outcome in acute chest infection and COPD/ILD population. Differentiation between infective and non-infective, COPD/ILD-related and non-COPD/ILD-related SSP may enable more personalized management.
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