ArticleJournal of thoracic disease2026
Perioperative fatigue after lung resection for pulmonary nodules and early-stage lung cancer: a systematic review and meta-analysis.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Fatigue is among the most common and function-limiting symptoms after lung resection, yet reported rates differ substantially because studies apply different instruments, thresholds, and assessment time points. This study aimed to synthesize the prevalence, time course, and correlations of postoperative fatigue following lung resection for pulmonary nodules/early-stage lung cancer. Methods: We searched PubMed/PubMed Central (PMC) and screened reference lists of relevant reviews and included studies from inception to January 15, 2026 and screened reference lists. Observational studies and trials reporting postoperative fatigue after lung resection were eligible. The primary quantitative outcome was the prevalence of clinically significant (moderate-to-severe) fatigue defined by validated cutoffs on 0-10 symptom scales [typically ≥4/10, a widely accepted threshold for moderate-to-severe symptoms in oncology; Patient Subjective Assessment-Lung (PSA-Lung) fatigue >3]. We performed random-effects meta-analysis on the logit scale and conducted prespecified subgroup analyses by time window (perioperative ≤1 month Results: Eleven studies (n=2,618 participants) met inclusion criteria; five studies provided extractable dichotomous data for clinically significant fatigue for meta-analysis. The pooled prevalence of clinically significant fatigue was 19.6% [95% confidence interval (CI): 11.6-31.3%; I Conclusions: Available evidence suggests that approximately one in five patients may experience clinically significant fatigue after lung resection, and persistence beyond 1 year is common. Standardized measurement (instrument and cutoff), consistent assessment windows, and fatigue-specific perioperative pathways are needed. Interpretation is limited by the small number of studies with extractable dichotomous data and by heterogeneity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.