ArticleFrontiers in neurology
The "brush sign": a novel and accessible CT marker for hematoma expansion in hypertensive intracerebral hemorrhage.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Patients with hypertensive intracerebral hemorrhage (ICH) are at risk for hematoma expansion (HE) in the early stages. Although the "spot sign" on computed tomography angiography (CTA) is a useful predictor of HE, the method has limitations, including low sensitivity and difficulty in identification. This study introduces a more recognizable and accessible "brush sign" on plain CT images following CTA examination and compares its effectiveness with the "spot sign" in predicting HE. Methods: Hypertensive ICH patients admitted to the Advanced Stroke Center of the hospital from January 2023 to December 2024 were retrospectively analyzed. This study evaluated sequential plain CT neuroimaging after CTA in these patients, defined the "brush sign," and identified two morphological types, namely "isolated" and "continuous." This study analyzed the correlations between the CTA "spot sign," "brush sign," and other clinical data with HE. Finally, the HE prediction efficiency of the "brush sign" and "spot sign" was compared using the receiver operating characteristic (ROC) analysis. Results: A total of 162 hypertensive ICH patients were enrolled, with 45 patients (27.8%) exhibiting HE. The spot, isolated brush, and continuous brush signs were observed in 48 (29.6%), 12 (7.4%), and 43 (26.5%) cases, respectively. The spot sign ( Conclusion: The "brush sign" can independently predict early HE in hypertensive ICH patients. The use of the continuous "brush sign" either alone or in combination with the "spot sign" demonstrates high accuracy for predicting HE. These markers can be used to stratify HE risk and suggest early intervention strategies for hypertensive ICH patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.