ArticleJournal of conservative dentistry and endodontics2026
Baseline serum 25-hydroxyvitamin D levels as a predictor of periapical healing and clinical success after primary root canal treatment: A prospective, observational, and cohort study.
Article in Journal of conservative dentistry and endodontics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Improbable healing in endodontics: a case series of favorable outcomes despite adverse prognostic conditions.BMC oral health · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
Background: Systemic host factors, such as serum 25-hydroxyvitamin D(25[OH]D), may influence periapical healing after root canal treatment (RCT); however, prospective clinical evidence remains limited. Aim: To evaluate whether baseline serum 25(OH)D levels predict periapical healing and 12-month clinical success following a primary RCT. Materials and Methods: Ninety systemically healthy adults (18-50 years old) requiring primary RCT of single-rooted teeth were enrolled. Participants were categorized as Vitamin D-deficient (<20 ng/mL) or sufficient (≥20 ng/mL). The lesion size, periapical index (PAI), pain (Visual Analog Scale), and clinical success were assessed at 6 and 12 months. Statistical Analysis: This comprised repeated-measures tests, independent group comparisons, receiver operating characteristic (ROC) analysis, and multivariable logistic regression adjusted for baseline lesion size, with Results: Both groups demonstrated significant improvement over time ( Conclusion: Baseline serum 25(OH)D sufficiency was associated with improved periapical healing and clinical success after primary RCT.
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