ArticleIranian journal of microbiology2026
Spectrum of central nervous system mycoses and antifungal susceptibility: a two-year retrospective analysis from a tertiary care hospital in India.
Article in Iranian journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Objectives: The frequency of central nervous system (CNS) fungal infections is rising, leading to increased mortality. These infections pose diagnostic challenges, and therapy depends on the specific fungal pathogen identified. Only a few studies from India have examined the spectrum of fungal pathogens causing CNS infections. The objective of this study was to analyze the clinical and microbiological diversity of fungal pathogens responsible for CNS infections. Materials and Methods: This was a retrospective study conducted at a tertiary care center in India from January 2023 to December 2024. The study included patients in whom fungi were isolated from cerebrospinal fluid, brain abscess pus, and paraspinal abscesses. Results: Nine fungal pathogens were identified during the study period. Three isolates were yeasts and six were molds. Brain abscess was the predominant clinical presentation. The yeast isolates included Conclusion: In the present study, nine fungal pathogens were isolated over a two-year period from varied clinical presentations. This highlights the rarity of the condition, which should not be overlooked.
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