Evidence map›Paper›PMID 42306302›Full record

ArticleFrontiers in cell and developmental biology2026

Hnrnpa1 is essential for early zebrafish development and lipid metabolism: insights from a novel zebrafish knockout model.

Lara U Jansen, Özge P Burhan, Alexander Hruscha, Janina Tokarz, Cornelia Prehn, Alexander Cecil, Jerzy Adamski, Christian Haass, Ting Sun, Stefan Bonn and 1 more

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In one paragraph

Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lara U JansenGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Özge P BurhanGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Alexander HruschaGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Janina TokarzHelmholtz Zentrum München, Neuherberg, Germany.
Cornelia PrehnHelmholtz Zentrum München, Neuherberg, Germany.
Alexander CecilHelmholtz Zentrum München, Neuherberg, Germany.
Jerzy AdamskiHelmholtz Zentrum München, Neuherberg, Germany.
Christian HaassGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Ting SunCenter for Molecular Neurobiology Hamburg (ZMNH), Hamburg, Germany.
Stefan BonnCenter for Molecular Neurobiology Hamburg (ZMNH), Hamburg, Germany.
Bettina SchmidGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA binding proteins have multiple diverse cellular functions and are often mis-regulated in disease. Despite their many cellular functions and implications in disease, very little is known about their physiological functions. Here we describe a novel zebrafish knockout model of the RNA binding proteins Hnrnpa1 and Hnrnpa3. Loss of Hnrnpa3 in zebrafish has no obvious morphological phenotype. Similarly, single mutants of the duplicated zebrafish

Indexed as

HNRNPA1metabolismnneurodegenerationRNA binding proteinzebrafish

Identifiers

PMID42306302
PMCPMC13265542

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.