ArticleReumatologia2026
Neuropathic pain in rheumatoid arthritis: prevalence and associated factors.
Article in Reumatologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: This study aimed to assess the prevalence of neuropathic pain in rheumatoid arthritis (RA) patients, and to identify associated factors. Material and methods: We conducted a cross-sectional study in patients with RA. Neuropathic pain was evaluated using the DN4 (Douleur Neuropathique 4) and PainDETECT scores. Agreement between the 2 questionnaires was estimated through Cohen's Results: A total of 121 patients with RA were included, with a mean age of 57 ±12.2 years, and a predominance of women (83%). The mean duration of RA was 16 ±1.0 years. The mean Disease Activity Score in 28 joints (DAS28) was 4.28 ±1.0, indicating moderate activity of the RA. According to the DN4 score, 61.2% of patients had neuropathic pain, and according to the PainDETECT score, 47.1% of patients were identified as having possible or likely neuropathic pain. Eighty-four patients (69.4%) had a positive DN4 score and/or a positive PainDETECT score. The coefficient of agreement k between the 2 tests was 0.233, indicating a fair agreement. Factors significantly associated with the presence of neuropathic pain were: female sex ( Conclusion: Our study suggests a potentially high prevalence of neuropathic pain in patients with RA, highlighting the need for early detection and appropriate management.
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