Evidence map›Paper›PMID 42306097›Full record

ArticleFrontiers in genetics2026

Pathogenic mechanisms of

XinRong Wang, YuYang Bai, XiaoYang Zuo, XiaoYin Lei, Xue Wang, Gang Zou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

XinRong WangThird Clinical Medical College, Ningxia Medical University, Yinchuan, Yinchuan, China.
YuYang BaiThird Clinical Medical College, Ningxia Medical University, Yinchuan, Yinchuan, China.
XiaoYang ZuoThird Clinical Medical College, Ningxia Medical University, Yinchuan, Yinchuan, China.
XiaoYin LeiThird Clinical Medical College, Ningxia Medical University, Yinchuan, Yinchuan, China.
Xue WangThird Clinical Medical College, Ningxia Medical University, Yinchuan, Yinchuan, China.
Gang ZouDepartment of Ophthalmology, Ningxia Eye Hospital, People's Hospital of Ningxia Hui Autonomous Region, Third Clinical School of Medicine, Ningxia Medical University, Yinchuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aims to identify pathogenic retinitis pigmentosa G Methods: A three-generation Chinese XLRP pedigree was enrolled for comprehensive ophthalmic examinations, including BCVA, OCT, FAF, and ERG. Whole-exome sequencing was performed on the proband to identify the pathogenic variants, followed by Sanger sequencing for validation in family members. To analyze the downstream molecular mechanisms, we analyzed a public single-cell RNA sequencing dataset (SRP535874) of Results: A hemizygous frameshift mutation (c.2476_2477del; p.R826Gfs*8) in the ORF15 region of Conclusion: We identify a previously reported but extremely rare

Indexed as

ciliary transportphotoreceptor differentiationRPGRsingle-cell RNA sequencingX-linked retinitis pigmentosa

Identifiers

PMID42306097
PMCPMC13268601

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.