Evidence map›Paper›PMID 42305834›Full record

ArticleJTCVS structural and endovascular2024

Impact of aortic root surgery during transcatheter aortic valve explant.

Alexander P Nissen, Stephanie K Tom, R Michael Reul, Elizabeth L Norton, Dale S Deas, Bradley G Leshnower, Gaetano Paone, W Brent Keeling, Woodrow J Farrington, Jonathan R Zurcher and 2 more

Abstract read
In one paragraph

Article in JTCVS structural and endovascular, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander P NissenDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Stephanie K TomDepartment of Surgery, Emory University School of Medicine, Atlanta, Ga.
R Michael ReulDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Elizabeth L NortonDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Dale S DeasDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Bradley G LeshnowerDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Gaetano PaoneDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
W Brent KeelingDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Woodrow J FarringtonDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Jonathan R ZurcherDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Robert A GuytonDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.
Kendra J GrubbDivision of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Ga.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcatheter aortic valve replacement (TAVR) explantation is currently the fastest-growing cardiac surgery procedure. Issues surrounding TAVR explantation and subsequent surgical aortic valve replacement (SAVR), specifically aortic root surgery, merit further investigation. Methods: A retrospective review of an institutional database identified cases of SAVR after TAVR, with or without concomitant aortic root operations, performed between January 1, 2014, and July 1, 2023, identifying 26 patients. Conventional statistical methods were used to compare groups. Results: The mean Society of Thoracic Surgeons predicted risk of mortality for aortic valve replacement was 11.1 ± 6.0% in our cohort. Eight of 26 patients (30.8%) had undergone prior cardiac surgery. Concomitant aortic root enlargement or replacement was required in 12 of the 26 patients (46.2%). The time from TAVR to removal was longer for those requiring root operations compared to those who did not (mean, 783 ± 908 days vs 492 ± 486 days; Conclusions: TAVR explant remains a high-risk procedure, although adding aortic root enlargement/replacement does not appear to amplify the short-term mortality risk when performed at an experienced institution. These results are important when considering lifetime management of aortic stenosis, particularly in low-risk patients likely to require multiple interventions.

Indexed as

aortic annulusaortic rootreoperationsurgical aortic valve replacementTAVR explanttranscatheter aortic valve replacement

Identifiers

PMID42305834
PMCPMC13244722

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.